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Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle

BACKGROUND: Pharmaceutical interventions for diabetes aim to control glycaemia and to prevent the development of complications, such as cardiovascular diseases. Some anti-hyperglycaemic drugs have been found to have adverse cardiovascular effects in their own right, limiting their therapeutic role....

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Bibliographic Details
Main Authors: Al-aryahi, Sefaa, Kamato, Danielle, Getachew, Robel, Zheng, Wenhua, Potocnik, Simon J, Cohen, Neale, Guidone, Daniel, Osman, Narin, Little, Peter J
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016772/
https://ncbi.nlm.nih.gov/pubmed/24731772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-80
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