Blocking Macrophage Leukotriene B(4) Prevents Endothelial Injury and Reverses Pulmonary Hypertension

Pulmonary hypertension (PH) is a serious condition that affects mainly young and middle-aged women, and its etiology is poorly understood. A prominent pathological feature of PH is accumulation of macrophages near the arterioles of the lung. In both clinical tissue and the SU5416 (SU)/athymic rat mo...

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Hlavní autoři: Tian, Wen, Jiang, Xinguo, Tamosiuniene, Rasa, Sung, Yon K., Qian, Jin, Dhillon, Gundeep, Gera, Lajos, Farkas, Laszlo, Rabinovitch, Marlene, Zamanian, Roham T., Inayathullah, Mohammed, Fridlib, Marina, Rajadas, Jayakumar, Peters-Golden, Marc, Voelkel, Norbert F., Nicolls, Mark R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016764/
https://ncbi.nlm.nih.gov/pubmed/23986401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006674
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