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Clusterin silencing inhibits proliferation and reduces invasion in human laryngeal squamous carcinoma cells

BACKGROUND: Clusterin is, in its major form, a secreted heterodimeric disulfide-linked glycoprotein (sCLU), which plays important roles in cell survival and death. In laryngeal squamous cell carcinomas (LSCC), sCLU is up-regulated and its expression is related to the invasiveness of these tumors. Th...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Qianjin, Cao, Weiyan, Su, Quancai, Liu, Zimin, Zhang, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016627/
https://ncbi.nlm.nih.gov/pubmed/24767179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-12-124
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