The unusual stability of the IS10 anti-sense RNA is critical for its function and is determined by the structure of its stem-domain.

IS10 transposition is regulated by an approximately 70 nt anti-sense RNA, RNA-OUT. RNA-OUT folds into a duplex 'stem-domain' topped by a loosely paired 'loop-domain'. The loop-domain is critical for RNA-RNA pairing per se; pairing initiates by interaction of the RNA-OUT loop with the 5' end of the t...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Case, C C, Roels, S M, Jensen, P D, Lee, J, Kleckner, N, Simons, R W
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2480235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08616.x
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