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Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani

BACKGROUND: Taxol (generic name paclitaxel), a plant-derived antineoplastic agent, used widely against breast, ovarian and lung cancer, was originally isolated from the bark of the Pacific yew, Taxus brevifolia. The limited supply of the drug has prompted efforts to find alternative sources, such as...

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Autori principali: Chakravarthi, Balabhadrapatruni VSK, Sujay, Ramanathan, Kuriakose, Gini C, Karande, Anjali A, Jayabaskaran, Chelliah
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016216/
https://ncbi.nlm.nih.gov/pubmed/24152585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-105
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