Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

Brain endothelial cells form a paracellular and transcellular barrier to many blood-borne solutes via tight junctions (TJs) and scarce endocytotic vesicles. The blood-brain barrier (BBB) plays a pivotal role in the healthy and diseased CNS. BBB damage after ischemic stroke contributes to increased m...

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Detalhes bibliográficos
Main Authors: Knowland, Daniel, Arac, Ahmet, Sekiguchi, Kohei, Hsu, Martin, Lutz, Sarah E., Perrino, John, Steinberg, Gary K., Barres, Ben A., Nimmerjahn, Axel, Agalliu, Dritan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016169/
https://ncbi.nlm.nih.gov/pubmed/24746419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.03.003
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