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Distinct docking and stabilization steps of the pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers

The closely related bacterial type II secretion (T2S) and type IV pilus (T4P) systems are sophisticated machines that assemble dynamic fibers promoting protein transport, motility or adhesion. Despite their essential role in virulence, the molecular mechanisms underlying helical fiber assembly remai...

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Detalhes bibliográficos
Main Authors: Nivaskumar, Mangayarkarasi, Bouvier, Guillaume, Campos, Manuel, Nadeau, Nathalie, Yu, Xiong, Egelman, Edward H., Nilges, Michael, Francetic, Olivera
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016124/
https://ncbi.nlm.nih.gov/pubmed/24685147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.001
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