Distinct docking and stabilization steps of the pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers

The closely related bacterial type II secretion (T2S) and type IV pilus (T4P) systems are sophisticated machines that assemble dynamic fibers promoting protein transport, motility or adhesion. Despite their essential role in virulence, the molecular mechanisms underlying helical fiber assembly remai...

Full description

Saved in:
Bibliographic Details
Main Authors: Nivaskumar, Mangayarkarasi, Bouvier, Guillaume, Campos, Manuel, Nadeau, Nathalie, Yu, Xiong, Egelman, Edward H., Nilges, Michael, Francetic, Olivera
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016124/
https://ncbi.nlm.nih.gov/pubmed/24685147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items