Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

The interaction between the U1 snRNP-specific U1 A protein and U1 snRNA has been analysed. The binding site for the protein on the RNA is shown to be in hairpin II, which extends from positions 48 to 91 in the RNA. Within this hairpin the evolutionarily conserved loop sequence is crucial for interac...

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Publié dans:	EMBO J
Auteurs principaux:	Scherly, D, Boelens, W, van Venrooij, W J, Dathan, N A, Hamm, J, Mattaj, I W
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401606/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2531658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08601.x
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