Perhexiline maleate in the treatment of fibrodysplasia ossificans progressiva: an open-labeled clinical trial

BACKGROUND: Currently, there are no effective medical treatment options to prevent the formation of heterotopic bones in fibrodysplasia ossificans progressiva (FOP). By the drug repositioning strategy, we confirmed that perhexiline maleate (Pex) potentially ameliorates heterotopic ossification in mo...

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Detalhes bibliográficos
Main Authors: Kitoh, Hiroshi, Achiwa, Masataka, Kaneko, Hiroshi, Mishima, Kenichi, Matsushita, Masaki, Kadono, Izumi, Horowitz, John D, Sallustio, Benedetta C, Ohno, Kinji, Ishiguro, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015865/
https://ncbi.nlm.nih.gov/pubmed/24131551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-8-163
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