GLP‐1 receptor agonist attenuates endoplasmic reticulum stress‐mediated β‐cell damage in Akita mice

Aims/Introduction:  Endoplasmic reticulum (ER) stress is one of the contributing factors in the development of type 2 diabetes. To investigate the cytoprotective effect of glucagon‐like peptide 1 receptor (GLP‐1R) signaling in vivo, we examined the action of exendin‐4 (Ex‐4), a potent GLP‐1R agonist...

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Autors principals: Yamane, Shunsuke, Hamamoto, Yoshiyuki, Harashima, Shin‐ichi, Harada, Norio, Hamasaki, Akihiro, Toyoda, Kentaro, Fujita, Kazuyo, Joo, Erina, Seino, Yutaka, Inagaki, Nobuya
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015545/
https://ncbi.nlm.nih.gov/pubmed/24843469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2010.00075.x
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