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Deciphering the functions and regulation of brain-enriched A-to-I RNA editing

Adenosine-to-inosine (A-to-I) RNA editing, in which genomically encoded adenosine is changed to inosine in RNA, is catalyzed by adenosine deaminase acting on RNA (ADAR). This fine-tuning mechanism is critical during normal development and diseases, particularly in relation to brain functions. A-to-I...

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Detalhes bibliográficos
Main Authors: Li, Jin Billy, Church, George M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015515/
https://ncbi.nlm.nih.gov/pubmed/24165678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3539
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