Activity of nicotinic acid substituted nicotinic acid adenine dinucleotide phosphate (NAADP) analogs in a human cell line: difference in specificity between human and sea urchin NAADP receptors

Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca(2+) mobilizing second messenger that has been identified. We have previously shown that NAADP analogs substituted at the 5-position of nicotinic acid were recognized by the sea urchin receptor at low concentration, whereas t...

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Autors principals: Ali, Ramadan A., Zhelay, Tetyana, Trabbic, Christopher J., Walseth, Timothy F., Slama, James T., Giovannucci, David R., Wall, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015339/
https://ncbi.nlm.nih.gov/pubmed/24439527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2013.12.004
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