MiR-370 sensitizes chronic myeloid leukemia K562 cells to homoharringtonine by targeting Forkhead box M1

BACKGROUND: Homoharringtonine (HHT) is a kind of cephalotaxus alkaloid used in traditional Chinese medicine. Although HHT has been successfully used as a therapeutic agent for leukemia, the drug resistance and toxicity are major concerns. MicroRNAs (miRNAs) have been identified to modulate cellular...

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Detalhes bibliográficos
Main Authors: Zhou, MinRan, Zeng, JiPing, Wang, XiaoMing, Guo, Qing, Huang, Tao, Shen, HaiYu, Fu, Yue, Wang, LiXiang, Jia, JiHui, Chen, ChunYan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015315/
https://ncbi.nlm.nih.gov/pubmed/24148180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-265
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