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Suppression of Murine Colitis and its Associated Cancer by Carcinoembryonic Antigen-Specific Regulatory T Cells

The adoptive transfer of regulatory T cells (Tregs) offers a promising strategy to combat pathologies that are characterized by aberrant immune activation, including graft rejection and autoinflammatory diseases. Expression of a chimeric antigen receptor (CAR) gene in Tregs redirects them to the sit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blat, Dan, Zigmond, Ehud, Alteber, Zoya, Waks, Tova, Eshhar, Zelig
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015241/
https://ncbi.nlm.nih.gov/pubmed/24686242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.41
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