Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

BACKGROUND: Cholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical outcomes of patients who received the CHP-NY-ESO-1 complex vaccine, Drug code: IMF-001. METHODS: Patients with advanced/metastatic esophageal...

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Bibliografiske detaljer
Main Authors: Kageyama, Shinichi, Wada, Hisashi, Muro, Kei, Niwa, Yasumasa, Ueda, Shugo, Miyata, Hiroshi, Takiguchi, Shuji, Sugino, Sahoko H, Miyahara, Yoshihiro, Ikeda, Hiroaki, Imai, Naoko, Sato, Eiichi, Yamada, Tomomi, Osako, Masaharu, Ohnishi, Mami, Harada, Naozumi, Hishida, Tadashi, Doki, Yuichiro, Shiku, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015172/
https://ncbi.nlm.nih.gov/pubmed/24093426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-246
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