Alcohol-preferring rats show decreased corticotropin-releasing hormone 2 receptor expression and differences in HPA activation compared to alcohol-nonpreferring rats

BACKGROUND: Corticotropin releasing hormone (CRH) and urocortins (UCNs) bind to corticotropin releasing hormone type 2 receptor (CRH-R2), a Gs protein-coupled receptor that plays an important role in modulation of anxiety and stress responses. The Crhr2 gene maps to a quantitative trait locus (QTL)...

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Autors principals: Yong, Weidong, Spence, John Paul, Eskay, Robert, Fitz, Stephanie D., Damadzic, Ruslan, Lai, Dongbing, Foroud, Tatiana, Carr, Lucinda G., Shekhar, Anantha, Chester, Julia A., Heilig, Markus, Liang, Tiebing
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015136/
https://ncbi.nlm.nih.gov/pubmed/24611993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12379
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