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Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily.

We report the three-dimensional structure of osteogenic protein 1 (OP-1, also known as bone morphogenetic protein 7) to 2.8-A resolution. OP-1 is a member of the transforming growth factor beta (TGF-beta) superfamily of proteins and is able to induce new bone formation in vivo. Members of this super...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Griffith, D L, Keck, P C, Sampath, T K, Rueger, D C, Carlson, W D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8570652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.2.878
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