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Parametric sensitivity analysis for biochemical reaction networks based on pathwise information theory

BACKGROUND: Stochastic modeling and simulation provide powerful predictive methods for the intrinsic understanding of fundamental mechanisms in complex biochemical networks. Typically, such mathematical models involve networks of coupled jump stochastic processes with a large number of parameters th...

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Autori principali: Pantazis, Yannis, Katsoulakis, Markos A, Vlachos, Dionisios G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015035/
https://ncbi.nlm.nih.gov/pubmed/24148216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-311
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