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Drosophila Sgs3 TATA: effects of point mutations on expression in vivo and protein binding in vitro with staged nuclear extracts.

The Drosophila salivary gland secretion protein gene, Sgs3, has a consensus TATA sequence and gives rise to abundant stage and tissue-specific transcripts. Two TATA point mutations (TAAA and TAGA) reduce transcript levels approximately 50-fold when assayed in transgenic flies. This effect is reflect...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Giangrande, A, Mettling, C, Martin, M, Ruiz, C, Richards, G
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1989
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401502/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583107/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08510.x
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