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Coupling of Two Non-processive Myosin 5c Dimers Enables Processive Stepping along Actin Filaments

Myosin 5c (Myo5c) is a low duty ratio, non-processive motor unable to move continuously along actin filaments though it is believed to participate in secretory vesicle trafficking in vertebrate cells. Here, we measured the ATPase kinetics of Myo5c dimers and tested the possibility that the coupling...

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Detalhes bibliográficos
Main Authors: Gunther, Laura K., Furuta, Ken'ya, Bao, Jianjun, Urbanowski, Monica K., Kojima, Hiroaki, White, Howard D., Sakamoto, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014986/
https://ncbi.nlm.nih.gov/pubmed/24809456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04907
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