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“Specificity Determinants” Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa

A new class of antimicrobial agents with lower rates of resistance and different targets is urgently needed because of the rapidly increasing resistance to classical antibiotics. Amphipathic cationic α-helical antimicrobial peptides (AMPs) represent such a class of compounds. In our previous studies...

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Detalhes bibliográficos
Main Authors: Jiang, Ziqing, Vasil, Adriana I., Vasil, Michael L., Hodges, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014698/
https://ncbi.nlm.nih.gov/pubmed/24670666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph7040366
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