Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule.

A murine T cell hybridoma with a receptor specific for the class I molecule H-2 Dd was transfected with an expressible cDNA for human CD4. Expression of the human class II MHC molecule HLA-DP on Dd-positive murine fibroblasts resulted in a greatly enhanced response of the CD4-positive T cell hybrido...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Lamarre, D, Capon, D J, Karp, D R, Gregory, T, Long, E O, Sékaly, R P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08487.x
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