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Excision products of the T cell receptor gene support a progressive rearrangement model of the alpha/delta locus.

We have cloned extrachromosomal circular DNAs containing T cell receptor (TCR) delta gene segments in adult mouse thymocytes and splenocytes. We find that the frequency of circular DNA clones carrying germline delta sequences is lower than that of J alpha probe-positive clones, possibly related to i...

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Takeshita, S, Toda, M, Yamagishi, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401453/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08486.x
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