Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct therapies for this disease. Here we show that the cytokine IL-27 plays a crucia...

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Main Authors: Liu, Francesca Diane M., Kenngott, Elisabeth E., Schröter, Micha F., Kühl, Anja, Jennrich, Silke, Watzlawick, Ralf, Hoffmann, Ute, Wolff, Thorsten, Norley, Stephen, Scheffold, Alexander, Stumhofer, Jason S., Saris, Christiaan J. M., Schwab, Jan M., Hunter, Christopher A., Debes, Gudrun F., Hamann, Alf
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014457/
https://ncbi.nlm.nih.gov/pubmed/24809349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004110
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