Timed Action of IL-27 Protects from Immunopathology while Preserving Defense in Influenza

Infection with influenza virus can result in massive pulmonary infiltration and potentially fatal immunopathology. Understanding the endogenous mechanisms that control immunopathology could provide a key to novel adjunct therapies for this disease. Here we show that the cytokine IL-27 plays a crucia...

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Detalhes bibliográficos
Main Authors: Liu, Francesca Diane M., Kenngott, Elisabeth E., Schröter, Micha F., Kühl, Anja, Jennrich, Silke, Watzlawick, Ralf, Hoffmann, Ute, Wolff, Thorsten, Norley, Stephen, Scheffold, Alexander, Stumhofer, Jason S., Saris, Christiaan J. M., Schwab, Jan M., Hunter, Christopher A., Debes, Gudrun F., Hamann, Alf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014457/
https://ncbi.nlm.nih.gov/pubmed/24809349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004110
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