An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation

Post-translational modifications of proteins regulate diverse cellular functions, with mounting evidence suggesting that hierarchical cross-talk between distinct modifications may fine-tune cellular responses. For example, in apoptosis, caspases promote cell death via cleavage of key structural and...

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Bibliografische gegevens
Hoofdauteurs: Turowec, Jacob P., Zukowski, Stephanie A., Knight, James D. R., Smalley, David M., Graves, Lee M., Johnson, Gary L., Li, Shawn S. C., Lajoie, Gilles A., Litchfield, David W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2014
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014278/
https://ncbi.nlm.nih.gov/pubmed/24556848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037374
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