The Acute Transcriptomic and Proteomic Response of HC-04 Hepatoma Cells to Hepatocyte Growth Factor and its Implications for Plasmodium falciparum Sporozoite Invasion

The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (<0.1%), poor understanding of steady-state HCC biology, and lack of appropriate tools for trace sample analysis. HC-04 is the only HCC that suppor...

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Bibliografiske detaljer
Main Authors: Tao, Dingyin, King, Jonas G., Tweedell, Rebecca E., Jost, Philipp J., Boddey, Justin A., Dinglasan, Rhoel R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014276/
https://ncbi.nlm.nih.gov/pubmed/24532842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.035584
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