Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays

BACKGROUND: Lung cancer patients with mutations in the epidermal growth factor receptor (EGFR) are primary candidates for EGFR-targeted therapy. Reliable analyses of such mutations have previously been possible only in tumour tissue. Here, we demonstrate that mutations can be detected in plasma samp...

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Detalhes bibliográficos
Main Authors: Weber, Britta, Meldgaard, Peter, Hager, Henrik, Wu, Lin, Wei, Wen, Tsai, Julie, Khalil, Azza, Nexo, Ebba, Sorensen, Boe S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014134/
https://ncbi.nlm.nih.gov/pubmed/24773774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-294
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