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Human Lactate Dehydrogenase A (LDHA) Rescues Mouse Ldhc-Null Sperm Function

By targeted disruption of the lactate dehydrogenase c (Ldhc) gene, we demonstrated that spermatozoa require Ldhc for capacitation, motility, and fertilizing capacity. Ldhc expression is restricted to the developing germ cells that, however, are apparently not compromised by the lack of the LDHC isoz...

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Autors principals: Tang, Huanghui, Duan, Chongwen, Bleher, Reiner, Goldberg, Erwin
Format: Artigo
Idioma:Inglês
Publicat: Society for the Study of Reproduction, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013880/
https://ncbi.nlm.nih.gov/pubmed/23467744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.107011
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