Functional Analysis of the Dioxin Response Elements (DREs) of the Murine CYP1A1 Gene Promoter: Beyond the Core DRE Sequence

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates the biological and toxicological effects of halogenated aromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). When activated by dioxin, the cytosolic AhR protein complex translocates int...

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Main Authors: Li, Shuaizhang, Pei, Xinhui, Zhang, Wen, Xie, Heidi Qunhui, Zhao, Bin
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013641/
https://ncbi.nlm.nih.gov/pubmed/24743890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15046475
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