Synthesis and conformational analysis of a series of galactosyl enkephalin analogues showing high analgesic activity.

Two galactosyl derivatives of [DMet2,Pro5] enkephalin-amide (compound 1), namely [DMet2,Pro5] enkephalin [N1.5-beta-D-galactopyranosyl] amide (compound 2) and O1.5-(beta-D-galactopyranosyl) [DMet2,Hyp5] enkephalin-amide (compound 3) have been synthesized. Such glycosylpeptides have been shown to be...

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Argitaratua izan da:	EMBO J
Egile Nagusiak:	Torres, J L, Pepermans, H, Valencia, G, Reig, F, García-Antón, J M, Van Binst, G
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 1989
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401360/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08442.x
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