Disruption of the temporally regulated cloaca endodermal β-catenin signaling causes anorectal malformations

The cloaca is temporally formed and eventually divided by the urorectal septum (URS) during urogenital and anorectal organ development. Although congenital malformations, such as anorectal malformations (ARMs), are frequently observed during this process, the underlying pathogenic mechanisms remain...

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Bibliographic Details
Main Authors: Miyagawa, S, Harada, M, Matsumaru, D, Tanaka, K, Inoue, C, Nakahara, C, Haraguchi, R, Matsushita, S, Suzuki, K, Nakagata, N, Ng, R C-L, Akita, K, Lui, V C-H, Yamada, G
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013517/
https://ncbi.nlm.nih.gov/pubmed/24632946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.21
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