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Dysregulation of Wnt inhibitory factor 1 (Wif1) expression resulted in aberrant Wnt-β-catenin signaling and cell death of the cloaca endoderm, and anorectal malformations

In mammalian urorectal development, the urorectal septum (urs) descends from the ventral body wall to the cloaca membrane (cm) to partition the cloaca into urogenital sinus and rectum. Defective urs growth results in human congenital anorectal malformations (ARMs), and their pathogenic mechanisms ar...

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Hlavní autoři: Ng, R C-L, Matsumaru, D, Ho, A S-H, Garcia-Barceló, M-M, Yuan, Z-W, Smith, D, Kodjabachian, L, Tam, P K-H, Yamada, G, Lui, V C-H
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013516/
https://ncbi.nlm.nih.gov/pubmed/24632949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.20
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