The −930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case–control study and gene–risk factors interactions

Reactive oxygen species (ROS) are involved in the pathogenesis of atherosclerosis and coronary artery disease (CAD). NADPH oxidases are the main source of ROS in the vasculature. p22phox is a critical component of vascular NADPH oxidases and is encoded by the CYBA (cytochrome b(245) alpha) gene. The...

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Hauptverfasser: Niemiec, Pawel, Nowak, Tomasz, Iwanicki, Tomasz, Krauze, Jolanta, Gorczynska-Kosiorz, Sylwia, Grzeszczak, Wladyslaw, Ochalska-Tyka, Anna, Zak, Iwona
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013450/
https://ncbi.nlm.nih.gov/pubmed/24477591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-014-3191-9
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