Identification and characterization of a drug sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae

Puromycin is an aminonucleoside antibiotic with structural similarity to aminoacyl tRNA. This structure allows the drug to bind the ribosomal A-site and incorporate into nascent polypeptides causing chain termination, ribosomal subunit dissociation, and widespread translational arrest at high concen...

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Detaylı Bibliyografya
Asıl Yazarlar: Cary, Gregory A., Yoon, Sung Hwan, Torres, Cecilia Garmendia, Wang, Kathie, Hays, Michelle, Ludlow, Catherine, Goodlett, David R., Dudley, Aimée M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013229/
https://ncbi.nlm.nih.gov/pubmed/24610064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/yea.3007
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