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Near Infrared Light-Triggered Drug Generation and Release from Gold Nanoparticle Carriers for Photodynamic Therapy

A photoprecursor Pc 227 is covalently bound onto gold nanoparticles (Au NPs) to produce the known photodynamic therapy (PDT) drug Pc 4 upon 660 nm photoirradiation. The photochemical formation of the photoproduct Pc 4 is identified by spectroscopy, chromatography, and mass spectrometry and its PDT e...

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Autors principals: Cheng, Yu, Doane, Tennyson L., Chuang, Chi-Hung, Ziady, Assem, Burda, Clemens
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013205/
https://ncbi.nlm.nih.gov/pubmed/24515950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201303329
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