Novel Anti-Apoptotic MicroRNAs 582-5p and 363 Promote Human Glioblastoma Stem Cell Survival via Direct Inhibition of Caspase 3, Caspase 9, and Bim

Glioblastoma is the most common and lethal primary brain tumor. Tumor initiation and recurrence are likely caused by a sub-population of glioblastoma stem cells, which may derive from mutated neural stem and precursor cells. Since CD133 is a stem cell marker for both normal brain and glioblastoma, a...

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Main Authors: Floyd, Desiree Hunt, Zhang, Ying, Dey, Bijan K., Kefas, Benjamin, Breit, Hannah, Marks, Kaitlyn, Dutta, Anindya, Herold-Mende, Christel, Synowitz, Michael, Glass, Rainer, Abounader, Roger, Purow, Benjamin W.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013090/
https://ncbi.nlm.nih.gov/pubmed/24805821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096239
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