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Real-World Efficiency of Pharmacogenetic Screening for Carbamazepine-Induced Severe Cutaneous Adverse Reactions
OBJECTIVES: We evaluated the cost and efficiency of routine HLA-B*15∶02 screening to prevent carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (CBZ-SJS/TEN) in Hong Kong. METHODS: Data were extracted from patients who commenced CBZ as the first-ever AED treatment or teste...
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013087/ https://ncbi.nlm.nih.gov/pubmed/24806465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096990 |
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