TIPE2 Negatively Regulates Inflammation by Switching Arginine Metabolism from Nitric Oxide Synthase to Arginase

TIPE2, the tumor necrosis factor (TNF)-alpha-induced protein 8-like 2 (TNFAIP8L2), plays an essential role in maintaining immune homeostasis. It is highly expressed in macrophages and negatively regulates inflammation through inhibiting Toll-like receptor signaling. In this paper, we utilized RAW264...

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Detalhes bibliográficos
Main Authors: Lou, Yunwei, Zhang, Guizhong, Geng, Minghong, Zhang, Wenqian, Cui, Jian, Liu, Suxia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013027/
https://ncbi.nlm.nih.gov/pubmed/24806446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096508
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