Assessing the Role of STAT3 in DC Differentiation and Autologous DC Immunotherapy in Mouse Models of GBM

Cellular microenvironments, particularly those found in tumors, elicit a tolerogenic DC phenotype which can attenuate immune responses. Central to this process is the STAT3-mediated signaling cascade. As a transcription factor and oncogene, STAT3 promotes the expression of genes which allow tumor ce...

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Autors principals: Assi, Hikmat, Espinosa, Jaclyn, Suprise, Sarah, Sofroniew, Michael, Doherty, Robert, Zamler, Daniel, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013007/
https://ncbi.nlm.nih.gov/pubmed/24806510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096318
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