Efficacy and Dose-Dependent Safety of Intra-Arterial Delivery of Mesenchymal Stem Cells in a Rodent Stroke Model

Intra-arterial (IA) delivery of mesenchymal stem cells (MSCs) for acute ischemic stroke is attractive for clinical translation. However, studies using rat model of stroke have demonstrated that IA MSCs delivery can decrease middle cerebral artery (MCA) flow, which may limit its clinical translation....

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Detalhes bibliográficos
Main Authors: Yavagal, Dileep R., Lin, Baowan, Raval, Ami P., Garza, Philip S., Dong, Chuanhui, Zhao, Weizhao, Rangel, Erika B., McNiece, Ian, Rundek, Tatjana, Sacco, Ralph L., Perez-Pinzon, Miguel, Hare, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012944/
https://ncbi.nlm.nih.gov/pubmed/24807059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093735
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