Bordetella pertussis adenylate cyclase: purification and characterization of the toxic form of the enzyme.

Bordetella pertussis produces a calmodulin-sensitive adenylate cyclase (AC) which is an essential virulence factor in mammalian pertussis. Here we report the purification and characterization of the toxic form of the enzyme, which penetrates eukaryotic cells and generates high levels of intracellula...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Rogel, A, Schultz, J E, Brownlie, R M, Coote, J G, Parton, R, Hanski, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401284/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555185/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08417.x
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