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Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22.

A 6.5 kb region of DNA from Streptomyces violaceoruber, which contains polyketide synthase (PKS) genes for production of the benzoisochromane quinone moiety of the antibiotic, granaticin, was cloned and sequenced. Of six open reading frames (ORFs) identified, four (ORFs 1-4) would be transcribed in...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Sherman, D H, Malpartida, F, Bibb, M J, Kieser, H M, Hopwood, D A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2583128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08413.x
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