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Exploiting Population Samples to Enhance Genome-Wide Association Studies of Disease

It is widely acknowledged that genome-wide association studies (GWAS) of complex human disease fail to explain a large portion of heritability, primarily due to lack of statistical power—a problem that is exacerbated when seeking detection of interactions of multiple genomic loci. An untapped source...

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Detalhes bibliográficos
Main Authors: Kaufman, Shachar, Rosset, Saharon
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012491/
https://ncbi.nlm.nih.gov/pubmed/24614931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.162511
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