Intermolecular disulfide bonding in IgM: effects of replacing cysteine residues in the mu heavy chain.

The conventional model of polymeric IgM depicts a unique structure in which the mu heavy chains and J chain are joined by well defined disulfide bonds involving cysteine residues at positions 337, 414 and 575 of the mu chain. To test this model, we have used site directed mutagenesis to produce IgM...

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Publié dans:	EMBO J
Auteurs principaux:	Davis, A C, Roux, K H, Pursey, J, Shulman, M J
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2511005/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08389.x
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