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Synthesis and Anti-Tuberculosis Activity of the Marine Natural Product Caulerpin and Its Analogues
Caulerpin (1a), a bis-indole alkaloid from the marine algal Caulerpa sp., was synthesized in three reaction steps with an overall yield of 11%. The caulerpin analogues (1b–1g) were prepared using the same synthetic pathway with overall yields between 3% and 8%. The key reaction involved a radical ox...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012461/ https://ncbi.nlm.nih.gov/pubmed/24681629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md12041757 |
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