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The Escherichia coli regulatory protein OxyR discriminates between methylated and unmethylated states of the phage Mu mom promoter.

Expression of the phage Mu mom gene is transcriptionally regulated by DNA methylation. Three GATC sites upstream of the mom promoter have to be methylated by the Escherichia coli deoxyadenosine methylase (Dam) to allow initiation of transcription. An E. coli dam strain was mutagenized with Tn5 in an...

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Publicat a:EMBO J
Autors principals: Bölker, M, Kahmann, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2551682/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08370.x
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