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Efficacy and Side Effects of Natalizumab Therapy in Patients with Multiple Sclerosis

Natalizumab (Nat) is a humanized monoclonal antibody used for the treatment of relapsing multiple sclerosis (MS). Nat inhibits lymphocyte migration via the blood brain barrier (BBB) by blockage of an integrin adhesion molecule, very late antigen 4. During the phase III clinical trials, it was shown...

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Detalhes bibliográficos
Main Authors: Hoepner, Robert, Faissner, Simon, Salmen, Anke, Gold, Ralf, Chan, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011812/
https://ncbi.nlm.nih.gov/pubmed/24855407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/JCNSD.S14049
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