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Haploinsufficiency of Def Activates p53-Dependent TGFβ Signalling and Causes Scar Formation after Partial Hepatectomy

The metazoan liver exhibits a remarkable capacity to regenerate lost liver mass without leaving a scar following partial hepatectomy (PH). Whilst previous studies have identified components of several different signaling pathways that are essential for activation of hepatocyte proliferation during l...

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Autors principals: Zhu, Zhihui, Chen, Jun, Xiong, Jing-Wei, Peng, Jinrong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011785/
https://ncbi.nlm.nih.gov/pubmed/24801718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096576
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