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Nucleosomes inhibit both transcriptional initiation and elongation by RNA polymerase III in vitro.

To examine the effect of nucleosomes on in vitro transcription, purified chicken erythrocyte core histones and plasmid DNA bearing the Xenopus 5S RNA gene were assembled into nucleosomes and used as templates for transcription in a Xenopus oocyte nuclear extract. Plasmids having a nucleosome incorpo...

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Bibliografiske detaljer
Udgivet i:EMBO J
Hovedforfatter: Morse, R H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2792088/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08362.x
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